Whenever you're in need of a lot of mouse clicking, Autoclick is an easy to use OS X app that takes care of it for you.
Autoclick can issue clicks at a fast rate (up to 50 clicks per second).
Clicking has never been any easier. Just start the Autoclick app, press Start and let it do all the clicking.
Click the "Basic"/"Advanced" button on the titlebar to enable or disable the advanced options.
NOTE: To buy Autoclick via the App Store an Apple account is required.